提升動物實驗的品質,降低動物不必要的痛苦和緊迫,如:強化操作技術、提供最適合動物居住的環境、適當的使用止痛藥及麻醉藥等。
動物實驗精緻化的最大的目的就是給動物更適合的飼養環境、更純熟的操作技術、更精準的實驗設計,以及更人道的實驗管理。也就是說,精緻化是一種態度,這種態度讓所有的學生、操作人員認知必須對動物夠好,必須要給動物最適宜的實驗環境。
Refinement refers to modifications of husbandry or experimental procedures to enhance animal well-being and minimize or eliminate pain and distress. While institutions and investigators should take all reasonable measures to eliminate pain and distress through refinement, IACUCs should understand that with some types of studies there may be either unforeseen or intended experimental outcomes that produce pain. These outcomes may or may not be eliminated based on the goals of the study.
台灣聯合大學系統信義榮譽講座編輯小組(譯)(2009)。研究倫理教學手冊(原作者:N. H. Steneck)。台灣聯合大學系統。(原著出版年:2007)
戴正德,李明濱,陳彥元,陳祖裕,秦咸靜,陳肇文,黃燦龍,韓志平,呂克桓,陳恆德,游彥城,許重義(2012)。人體研究倫理的理念與實踐。教育部。
National Research Council (US) Committee for the Update of the Guide for the Care and Use of Laboratory Animals. (2011). Guide for the Care and Use of Laboratory Animals. 8th edition. Washington (DC): National Academies Press (US)
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